Galo Garcia (Reiter Lab) and Xiaoyu Shi show us how the ciliary gate is organized and how that goes wrong in disease.
QBI held a competition to give away 1.1 million dollars for bold ideas and basic research in cancer and psychiatry. Four grants and four fellowships were awarded to the best collaborative ideas that merged both basic and clinical research. Jeremy Reiter and David Raleigh proposed a bold idea in cancer: How fats cause cancer: Lipids in the primary cilium activate oncogenic Hedgehog signaling.
We are delighted to share the news that Peter Walter, PhD, professor and Howard Hughes Investigator in the School of Medicine Department of Biochemistry and Biophysics, has received a 2018 Breakthrough Prize in Life Sciences. This award recognizes him for "elucidating the unfolded protein response, a cellular quality-control system that detects disease-causing unfolded proteins and directs cells to take corrective measures."